550 - Acute Kidney Injury and Nutrition in Patients with Congenital Heart Disease
Friday, April 24, 2026
5:30pm - 8:00pm ET
Publication Number: 1529.550
Savannah Foster, UNT Health Texas College of Osteopathic Medicine, Fort Worth, TX, United States; Malik Childs, UNT Health Texas College of Osteopathic Medicine, Mesquite, TX, United States; Chris Tsao, Cook Children's Medical Center, Southlake, TX, United States; Fadeke Ogunyankin, Cook Children's Health Care System, Fort Worth, TX, United States; Vinai Modem, TCU Burnett School of Medicine, Fort Worth, TX, United States; Lane T. Lanier, Cook Children's Medical Center, Fort Worth, TX, United States
Medical Student UNT Health Texas College of Osteopathic Medicine Fort Worth, Texas, United States
Background: Acute kidney injury (AKI) is a common complication in pediatric patients with congenital heart disease (CHD) undergoing cardiopulmonary bypass (CPB), contributing to increased morbidity, mortality, and nutritional challenges. This study aims to determine the incidence of AKI after cardiac surgery in CHD patients admitted to a single center CICU and compare time to achieve full enteral nutrition between those with and without AKI. We hypothesize that patients aged 0–6 months with CHD and AKI will achieve full enteral nutrition goals significantly later than those without AKI. Objective: To evaluate nutritional outcomes in patients who developed AKI after cardiac surgery compared to those without AKI. Design/Methods: Electronic medical records of 285 pediatric patients 0-6 months of age between 2018 and 2025 who underwent cardiac surgery at Cook Children’s Medical Center (CCMC) were analyzed. Patients who died within 24 hours upon admission to the cardiac intensive care unit and those without nutrition documentation were excluded. AKI was defined by KDIGO guidelines for creatinine and/or urine output. Full nutrition was defined in 2 ventricle physiology as 100 kcal/kg/day and in single ventricle physiology as 120 kcal/kg/day. Results: Two hundred eighty-five patients were included in the study. One hundred-twelve patients met criteria for AKI. Patients with AKI had longer CPB times but cross clamp times were not longer. Patients with AKI had longer modified ultrafiltration (MUF) time, but not more MUF volume/kg. Time from surgery to 100 ml/kg of enteral volume was longer in the AKI group. Time to full enteral nutrition in 2 ventricle physiology patients was significantly longer in the AKI group. Time to full enteral nutrition in single ventricle physiology was not significantly longer in the AKI group than the non-AKI group.
Conclusion(s): Pediatric patients aged 0–6 months with congenital heart disease (CHD) who develop acute kidney injury (AKI) following CPB surgery reach full enteral volume later than those without AKI. Patients with 2 ventricle physiology and AKI reach full enteral nutrition later than those without AKI. Our findings indicate the impact of AKI on meeting nutritional requirements in this cohort.
