How Variants of Uncertain Significance Impact Clinical Care

Shiv Ayappa, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Steven Joffe, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States; Anne-Marie Laberge, CHU Sainte-Justine, Montreal, PQ, Canada; Russell Nye, Childrens Hospital of Philadelphia, Philadelphia, PA, United States; Molly Hess, Childrens Hospital of Philadelphia, Philadelphia, PA, United States; Katharine P. Callahan, Children's Hospital of Philadelphia, Haddonfield, NJ, United States